Whole-cell currents in isolated resting Necturus gastric oxynticopeptic cells.
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چکیده
منابع مشابه
[Extracellular calcium modulates the whole cell potassium currents in Deiters cells isolated from guinea pig cochlea].
To study the modulatory effect of extracellular calcium on the whole cell K(+) currents (I(K)) in isolated Deiters cells, the whole cell K(+) currents were recorded when Deiters cells bathed in normal physiological solutions and calcium-free saline, respectively. The electrophysiological characteristics of I(K) currents were then analyzed with the patch clamp technique. Removing extracellular c...
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To isolate inward Ca2+ currents in GH3 rat pituitary cells, an inward Na+ current as well as two outward K+ currents, a transient voltage-dependent current (IKV) and a slowly rising Ca2+-activated current (IKCa), must be suppressed. Blockage of these outward currents, usually achieved by replacement of intracellular K+ with Cs+, reveals sustained inward currents. Selective blockage of either K+...
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Luminal acid causes intracellular acidification in the gastric epithelium, but the mechanism by which H(+) enters surface cells remains obscure. This study addressed the problem by assessing how different acids affect intracellular pH in gastric surface cells. Isolated Necturus maculosus antral mucosa was exposed to HCl, HNO(3), H(2)SO(4), and H(3)PO(4) at pH 2.30. Intracellular pH was measured...
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Mechanoelectric transduction can initiate cardiac arrhythmias. To examine the origins of this effect at the cellular level, we made whole cell voltage-clamp recordings from acutely isolated rat ventricular myocytes under controlled strain. Longitudinal stretch elicited noninactivating inward cationic currents that increased the action potential duration. These stretch-activated currents could b...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1993
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1993.sp019584